LSU vs. Vanderbilt odds, line: 2020 college football picks, Week 5 predictions from proven computer model

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Get ready for an SEC battle as the Vanderbilt Commodores and the LSU Tigers will face off at 7:30 p.m. ET on Saturday at Vanderbilt Stadium. Vanderbilt is 0-1 overall and 0-0 at home, while LSU is 0-1 overall and 0-0 on the road. LSU has won eight straight against Vanderbilt and has the 23-7-1 all-time edge in the series.

The Tigers are favored by 20.5-points in the latest Vanderbilt vs. LSU odds from William Hill. The over-under for total points is set at 49.5. Before entering any LSU vs. Vanderbilt picks, you’ll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $4,000 for $100 players on its top-rated college football picks against the spread. It’s a sizzling 16-2 on top-rated picks through four weeks of the 2020 college football season, returning over $1,100 in profit already. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Vanderbilt vs. LSU. You can head to SportsLine to see its picks. Here are several college football odds for LSU vs. Vanderbilt:

  • LSU vs. Vanderbilt spread: Vanderbilt +20.5
  • LSU vs. Vanderbilt over-under: 49.5 points
  • LSU vs. Vanderbilt money line: Vanderbilt +800, LSU -1300

What you need to know about Vanderbilt

Vanderbilt nearly pulled off one of the biggest upsets on the Week 4 schedule, pushing Texas A&M to the wire before the Aggies ultimately won 17-12. The Commodores (+31) covered the spread with plenty of room to spare. Vanderbilt used its talented defensive front to get solid pressure in the game. 

The Commodores will need to do that against an LSU offense that struggled with