Foundation to Fight H-ABC, University of Massachusetts Medical School and Yale University Initiate Gene Therapy Study Targeting Cure for Rare Disease

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ROCKVILLE, Md., Oct. 13, 2020 /PRNewswire/ — Foundation to Fight H-ABC, a non-profit organization dedicated to increasing awareness and driving development of a cure for the degenerative children’s disease, H-ABC, today announced a sponsored research agreement with the University of Massachusetts Medical School and Yale University to advance a targeted gene therapy for H-ABC.

“We have high hopes to quickly prove efficacy with this approach to move research forward and find a permanent cure for this devastating disease,” said Michele Sloan, Co-Founder, Foundation to Fight H-ABC.

H-ABC (hypomyelination with atrophy of the basal ganglia and cerebellum) belongs to a group of conditions called leukodystrophies, diseases that affect the white matter of the brain. These diseases disrupt the growth or maintenance of the myelin sheath, a protective layer that insulates nerve cells and allows for the transmission of messages between cells.

Caused by a mutation in the TUBB4A gene, H-ABC is a rare genetic disorder that affects certain parts of the brain—specifically the basal ganglia and the cerebellum, which control movement. H-ABC targets these important structures, reducing both their size and function. As a result, children who suffer from H-ABC often experience motor problems, cannot walk, talk, or sit on their own. Currently, there is no known cure for this disabling and life-threatening condition.

The teams of Dr. Guangping Gao (University of Massachusetts Medical School) and Dr. Karel Liem (Yale School of Medicine) will combine extensive expertise in the fields of Adeno-associated virus (AAV), a platform for gene delivery for the treatment of a variety of human diseases and H-ABC disease models, to develop AAV vectors to silence or outcompete the mutated TUBB4A gene.

“To date, AAV-based gene delivery system is the vector of choice for in vivo gene therapy of many currently untreatable rare diseases including H-ABC,” said Guangping Gao,


University Hospitals Parma Medical Center unveils high-tech robotic surgery

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PARMA, Ohio — It was only a matter of time before 21st century medicine included the introduction of robotic surgery.

Apparently, the future has arrived with the ongoing $27.5 million renovation of the University Hospitals Parma Medical Center’s Surgery Department, including the recent addition of the high-tech da Vinci Xi robot, which went into operation two weeks ago.

“It is a significant step forward,” said Dr. David Linz, a general surgeon based at UH Parma Medical Center. “Robotic surgery makes minimally invasive surgery better, safer and more precise. It’s taking laparoscopic surgery to another level.”

The da Vinci Xi surgical system enhances surgical performance by creating a natural extension of the surgeon’s eyes and hands. Previously in laparoscopic surgery, the surgeon would view the case on a monitor while manipulating the surgical instruments with his hands while standing at the operating table.

“Robotics allow you to have much more control of the instruments,” Linz said. “Traditionally with laparoscopic, you’re standing next to the patient bedside operating and looking up at a monitor that is 6 feet away.

“Robotically, you’re at the console with high-definition, 3-D vision. You’re totally emerged in the visual field. You can get precise down to millimeters. You can do very fine dissections that are really difficult to do with traditional laparoscopic. It’s very steady, very smooth and the risk of injury is much less,” he said.

In robotic surgery, the arms of the robot are positioned over the patient. The surgeon controls the robot’s arms while sitting at a control console.

The advanced surgical system can be used for a minimally invasive surgical approach to complex diseases and conditions in urology, thoracic, cardiac, colorectal, gynecology and general surgery.

“Robotic surgery allows us unprecedented dexterity and precision in surgery,” said urologist Dr. David Turk, who is


University of Toledo Medical Center, University of Toledo Physicians Sign Network Agreements with Humana

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Leading health and well-being company Humana Inc. (NYSE: HUM) announced today it has signed Medicare and commercial plan network agreements with University of Toledo Medical Center (UTMC) and University of Toledo Physicians (UTP).

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20200930005109/en/

The contracts are in effect for certain Humana Medicare Advantage Health Maintenance Organization (HMO), Preferred Provider Organization (PPO), and Private Fee-for-Service (PFFS) health plans and Humana commercial HMO and PPO health plans in Ohio and Michigan. Plan members have in-network access:

  • At UTMC, a community-focused teaching hospital in northwest Ohio. The 247-bed hospital is a major patient-care referral and teaching facility.

  • With more than 280 UTP physicians in an array of specialties and subspecialties. UTP is a multi-specialty faculty practice group affiliated with UTMC.

“This agreement is a reflection of our commitment of more than 50 years to offer quality health care near where people live and work,” said UTMC CEO Rick Swaine. “UTMC is pleased to be an in-network option for Humana members. We look forward to them placing their trust in us as we care for them and help them with their health care needs.”

“We are aligned with Humana in our dedication to compassionate, patient-centered health care, and pleased to join together to help its members be as healthy as they can,” said UTP Chief Physician Executive Kris Brickman, M.D. “Broadening access to care is important to all of us at UTP, particularly during these difficult times.”

“Expanding options for care has never been more imperative than it is today, given the challenges we face as the coronavirus pandemic continues,” said Humana Regional President Kathie Mancini. “Humana looks forward to collaborating with UTMC and University of Toledo Physicians in support of the


Career Opportunities In Medical Coding And Billing

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Career Alternatives In Medical Coding And Billing

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Challenges and competitors are the a part of right now’s society, and therefore, Career Planning is the only activity, which may guide us to do what we need to do in our life, quite than simply aimlessly changing job all the time in future.

Some facilitators really feel that older learners’ time on the job is limited and unwilling to study expertise or new expertise. It assist us figuring out the character of the jobs that interest us, reminiscent of instructional requirements, salary, working situations, fringe benefits, promotion probabilities, future prospectus, and …